At the most intense level (similar to blood flow restriction or overtraining), everyone felt pain — even though there was no damage, no injury, and no emotional context.
💡 Why this matters:
 It proves that your body alone — without needing an injury or a psychological trigger — can send signals up to the brain that are strong enough to cause real pain.
🚨 Bottom-Up Pain, No Damage Required
This graph breaks the myth that pain only happens when:
- You’re hurt 
- Your brain “misinterprets” safe signals as dangerous (which is the focus of many modern pain education models) 
Instead, it shows:
Sometimes your body chemistry alone can push the system into pain — even if there’s nothing structurally wrong.
Your muscles and tissues have sensors that detect acidity, fatigue, and other signs of internal stress. When those sensors are triggered enough, they fire pain signals straight up the spinal cord to your brain.
No story. No emotion. Just raw, bottom-up input.
🧭 So What’s the Takeaway?
If you're in pain and nothing seems “wrong” on your scans, you’re not imagining it.
 Your body might just be in a state of imbalance, and the signals are getting loud.
This is why recovery often needs more than mindset work — it needs real support for your physiology:
 hydration, breathing, rest, movement, and rhythm.
So… What Do You Do With This?
If pain is your body’s call for balance, then managing pain becomes less about “fixing” and more about listening + supporting.
Here’s how that might look in real life:
1. Zoom Out from the “Injury” Narrative
If your pain isn’t linked to a fresh injury, consider:
- Am I underslept? 
- Stressed or emotionally stretched? 
- Under-recovered from training or work? 
- Eating or drinking in ways that support or stress me? 
Sometimes, it’s not about the area that hurts — it’s about the system being overloaded.
2. Respect Your Chemistry
That graph didn’t lie:
 Your pain may just be your body saying,
“Hey, it’s getting acidic and inflamed in here. Can we chill?”
So…
- Hydrate well 
- Prioritize sleep 
- Breathe slowly, especially under pressure 
- Move gently (to encourage circulation, not exhaustion) 
3. Feel First, Fix Later
Instead of immediately chasing solutions, try noticing what your body is asking for.
 Sometimes it’s rest.
 Sometimes it’s gentle movement.
 Sometimes it’s just a moment to breathe and regroup.
Pain is often louder when the system is overwhelmed and under-heard.
Final Thought
Pain is real. It can be awful, disorienting, exhausting.
But it’s not always damage.
 It’s often information. And your job isn’t to silence it — it’s to tune in, understand it, and respond wisely.
As Lao Tzu said:
 “Do you have the patience to wait until your mud settles and the water is clear?”
That’s what self-care can be when we treat pain as a guide, not a glitch.
So next time your body whispers (or yells),
 Don’t just ask “What’s wrong with me?”
 Ask:
“What is my body trying to say — and how can I support it today?”
🔗 Exogenously Applied Muscle Metabolites Synergistically Evoke Sensations of Muscle Fatigue and Pain in Human Subjects
 Authors: Kelly, L.A., et al.
 Journal: The Journal of Physiology (2013)
Want to learn more and see how this makes sense through a case study ?  Read on…
🎯 Case Study: Mark’s Lower Back Flare-Up and the Model That Finally Made Sense
Mark, a 44-year-old graphic designer and father of two, has had on-and-off lower back pain for about five years. He’s fit, doesn’t sit too much, and has no major injuries in his history.
But one week, after a few late nights, some emotional stress at home, and pushing through a few intense gym sessions, he wakes up and…
 BAM — his lower back locks up again. Sharp, aching pain. Muscle tightness. Fear floods in.
Here’s how three common pain models would explain what’s going on — and how only one of them actually helped Mark feel seen and supported.
🩻 1. The Biomedical Model
What it says:
“You probably strained something again. Maybe your disc or facet joint is irritated. Better stop lifting and get some scans.”
What Mark does:
 He rests, pops anti-inflammatories, and stops training altogether. His scan shows a mild disc bulge (which he already knew about). Nothing new, but now he’s more afraid.
Result:
 Frustration, fear of re-injury, and no real answers. The pain slowly fades, but the anxiety remains.
🧠 2. The Pain Neuroscience Education (PNE) Model
What it says:
“Pain doesn’t mean damage. Your brain is just interpreting signals as dangerous because of stress or past experiences. Try reframing your thoughts and keep moving.”
What Mark does:
 He tries not to catastrophize. He tells himself “I’m safe.” He walks. He does a few gentle stretches and tries mindfulness. It helps… a little.
But deep down, he still feels like something in his body is off.
 He’s told “trust the process,” but the pain lingers. He starts doubting himself.
Result:
 Less fear, more confusion. He's doing “everything right,” yet still feels pain.
🌡 3. The Homeostatic Model (Bud Craig’s Approach)
What it says:
“Your pain is real. And your body is telling you something is out of balance — not broken, but dysregulated.”
It’s not just your thoughts. It’s your chemistry:
These all impact your body’s internal signals — and when the system gets overwhelmed, your brain sends the message: PAIN.
What Mark does:
 He reflects.
 “Ah — I’ve been skipping sleep. Stress is high. I trained hard but didn’t recover.”
 He doesn’t panic. He doesn’t stop moving. But he also doesn’t push through.
Instead, he:
- Adjusts his training for the week 
- Prioritizes rest and hydration 
- Focuses on steady breathing and slow walking 
- Eats anti-inflammatory meals 
- Lets his system settle 
Result:
 Within a few days, the pain eases without fear. He feels more confident, not because he ignored the pain — but because he listened to it.
✅ Takeaway: Pain as a Homeostatic Emotion
Mark’s back wasn’t “broken” — his body was overloaded.
The biomedical model told him he was fragile.
 The PNE model told him it was just his brain.
 The homeostatic model? It told him his body and brain were working together to send a useful signal.
And that changed everything.